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Antibiotic-associated colitis in orthopaedic patients
International Orthopaedics
|January 1, 1996
Summary
Antibiotic-associated colitis occurred in 23 orthopedic patients, often linked to clindamycin. Most patients recovered after treatment adjustments or discontinuation of the inciting antibiotic.
Area of Science:
- Medicine
- Infectious Diseases
- Gastroenterology
Background:
- Antibiotic-associated colitis (AAC) is a significant clinical concern.
- Orthopaedic patients are susceptible due to common antibiotic prophylaxis and treatment.
Purpose of the Study:
- To investigate the incidence, clinical presentation, and management of antibiotic-associated colitis in orthopaedic patients.
Main Methods:
- Retrospective analysis of 23 orthopaedic patients diagnosed with AAC.
- Review of patient symptoms, causative antibiotics, and treatment interventions.
Main Results:
- Clindamycin was the most frequent causative agent (19/23 patients).
- Symptoms ranged from abdominal discomfort to fever and elevated inflammatory markers.
- Most patients (22/23) were successfully treated by modifying antibiotic regimens or discontinuing the offending agent.
Conclusions:
- Antibiotic-associated colitis is a notable complication in orthopaedic surgery patients.
- Prompt recognition and appropriate management of antibiotic-associated colitis are crucial for patient recovery.