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Rodent parvovirus infections

R O Jacoby1, L J Ball-Goodrich, D G Besselsen

  • 1Section of Comparative Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.

Laboratory Animal Science
|August 1, 1996
PubMed
Summary

Rodent parvoviruses are common in lab animals, impacting research. New strains increase diversity, posing challenges for detection and prevention.

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Area of Science:

  • Veterinary Virology
  • Laboratory Animal Science

Background:

  • Rodent parvoviruses are prevalent infectious agents in laboratory animals.
  • These viruses significantly hinder the reliability of rodent-based research.
  • Previously known strains include minute virus of mice, rat virus, and H-1 virus.

Purpose of the Study:

  • To review current knowledge on rodent parvoviruses.
  • To highlight the impact of newly identified parvovirus strains.
  • To address challenges in detecting, preventing, and eliminating infections.

Main Methods:

  • Literature review of rodent parvovirus research.
  • Summary of current knowledge on parvovirus infections.
  • Focus on recently isolated and distinct parvovirus strains.

Main Results:

  • The diversity of rodent parvoviruses has increased with new isolates.
  • These novel strains are biologically and antigenically distinct.
  • Increased diversity presents challenges for research integrity and infection control.

Conclusions:

  • Understanding the expanded diversity of rodent parvoviruses is crucial.
  • New strains necessitate updated strategies for detection and control.
  • Effective management of parvovirus infections is vital for research reproducibility.

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