Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Association between reduced cuff leak volume and postextubation stridor

R L Miller1, R P Cole

  • 1Department of Medicine, Columbia-Presbyterian Medical Center, New York, NY 10032, USA.

Chest
|October 1, 1996
PubMed
Summary

Reduced endotracheal tube cuff leak volume predicts postextubation stridor risk in ICU patients. A cuff leak volume below 110 mL indicates a higher likelihood of stridor following extubation.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Barium ion sensing with IPG K<sup>+</sup> molecular probes.

The Analyst·2025
Same author

Fluorescence imaging of individual ions and molecules in pressurized noble gases for barium tagging in <sup>136</sup>Xe.

Nature communications·2024
Same author

Demonstration of event position reconstruction based on diffusion in the NEXT-white detector.

The European physical journal. C, Particles and fields·2024
Same author

Mechanism of internal fertilization in Pegea socia (Tunicata, Thaliacea), a salp with a solid oviduct.

Journal of morphology·2018
Same author

Skin closure in thin-skinned individuals using a continuous suture.

Journal of plastic, reconstructive & aesthetic surgery : JPRAS·2017
Same author

Effects of Coralliophila violacea on tissue loss in the scleractinian corals Porites spp. depend on host response.

Diseases of aquatic organisms·2016

Area of Science:

  • Critical Care Medicine
  • Pulmonology
  • Anesthesiology

Background:

  • Intubation-induced laryngotracheal injury or edema can narrow the airway, increasing postextubation stridor risk.
  • An audible air leak around the endotracheal tube cuff, when deflated, is a known marker for laryngotracheal edema in high-risk patients.

Purpose of the Study:

  • To quantify cuff leak volume in a general medical intensive care unit (ICU) population.
  • To correlate cuff leak volume with the likelihood of developing postextubation stridor.

Main Methods:

  • Cuff leak volume was measured within 24 hours of initiating and terminating mechanical ventilation.
  • This volume was defined as the difference between inspiratory and averaged expiratory tidal volumes with the endotracheal tube cuff deflated.

Related Experiment Videos

Main Results:

  • In 100 intubations, mean preextubation cuff leak volume was 349 ± 163 mL.
  • Patients who developed postextubation stridor had a significantly lower mean cuff leak volume (180 ± 157 mL) compared to those who did not (360 ± 157 mL; p = 0.012).
  • A cuff leak volume < 110 mL had a positive predictive value of 0.80 for stridor, while a volume > 110 mL had a negative predictive value of 0.98 for stridor, with 0.99 specificity.

Conclusions:

  • Reduced cuff leak volume before extubation identifies patients at increased risk for postextubation stridor.
  • This measurement serves as a valuable tool for predicting stridor in the ICU setting.