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Related Experiment Videos

Nutritional issues in cancer management

A Laviano1, M M Meguid

  • 1Department of Surgery, University Hospital, SUNY Health Science Center, Syracuse 13210, USA.

Nutrition (Burbank, Los Angeles County, Calif.)
|May 1, 1996
PubMed
Summary
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Diet and nutrition significantly impact cancer development and treatment. While standard nutritional support has limitations, novel nutritional therapies show promise for improving outcomes in cancer patients.

Area of Science:

  • Oncology
  • Nutritional Science
  • Metabolism

Background:

  • Approximately 30% of Western cancers are diet-related.
  • Malignancy negatively impacts patient nutritional status, increasing morbidity and mortality.
  • Standard nutritional support (enteral and parenteral) may not sufficiently improve outcomes in malnourished cancer patients due to metabolic changes.

Purpose of the Study:

  • To investigate the relationship between nutrition and cancer.
  • To examine the role of nutrition in cancer initiation, promotion, and treatment.
  • To evaluate the effectiveness of nutritional support and novel therapies in cancer care.

Main Methods:

  • Literature review of English-language studies published in the last 25 years.
  • Searches conducted using MEDLINE, bibliographies, and expert consultation.

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  • Inclusion of in vitro and in vivo controlled studies on nutritional factors in cancer prevention and treatment.

    • Main Results:

    • Diet is a significant factor in cancer development and progression.
    • Cancer significantly compromises nutritional status, affecting patient outcomes.
    • Emerging nutritional-pharmacologic agents show potential in improving metabolic derangements and patient outcomes.

    Conclusions:

    • Dietary interventions and nutritional-pharmacologic therapy can be effective adjuncts in managing symptoms for cancer patients.
    • Further research into advanced nutritional strategies is warranted for cancer care.
    • Optimizing nutritional status is crucial for improving the prognosis of cancer patients.