Non-rubeotic angle-closure glaucoma associated with ciliary medulloepithelioma

Non-rubeotic angle-closure glaucoma associated with ciliary medulloepithelioma was reported in a 3-year-old boy. On the first visit, a free-floating white mass was observed in the anterior chamber of his right eye. The mass disappeared spontaneously after 5 months of observation. One year later, angle-closure glaucoma with peripheral anterior synechia occurred in the same eye and intraocular pressure rose to 55 mmHg. After glaucoma surgery, the white mass appeared again in the anterior chamber of his right eye. By cycloscopy, numerous small grayish-white masses could be seen on the ciliary body and in the posterior chamber. Histopathological examination of one mass confirmed medulloepithelioma and the eye was enucleated. Disseminated tumor cells in the anterior chamber had caused the cornea and the peripheral iris to adhere to each other, resulting in the formation of peripheral anterior synechia.