Related Experiment Videos
False-positive serologic test resulting from a probable yeast infection in a chimpanzee
1Hepatitis Viruses Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892-0740, USA. Theller@atlas.niaid.nih.gov
Clinical and Diagnostic Laboratory Immunology
|September 1, 1996
Abstract:
Sera used to identify putative hepatitis E viral proteins expressed in Pischia pastoris produced a false-positive reaction because of antibodies to a yeast protein. This report illustrates a potential problem when serological reagents are used in combination with recombinant proteins expressed in yeast.