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Crystal and molecular structure of a histo-blood group antigen involved in cell adhesion: the Lewis x trisaccharide
S Pérez1, N Mouhous-Riou, N E Nifant'ev
1Ingeniérie Moléculaire, Institut National de la Recherche Agronomique, Nantes, France.
Glycobiology
|July 1, 1996
Abstract:
This work describes the first crystal structure ever reported of a histo-blood group carbohydrate antigen: Le(x). This study provides a detailed description of the conformation of two crystallographic independent molecules in a highly hydrated environment along with their hydrogen bonding properties and packing features. Some interactions observed between adjacent trisaccharides can provide the basis for involvement of Le(x)-Le(x) interactions in cell-cell adhesion.