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Cellular response in the cerebellum after midline traumatic brain injury in the rat
A E Mautes1, K Fukuda, L J Noble
1Department of Neurosurgery, University of California, San Francisco, USA.
Neuroscience Letters
|August 23, 1996
Abstract:
We evaluated the response of microglia and Purkinje cells in the cerebellum at 1, 2, 3, 7 and 10 days after a midline fluid percussion brain injury. There was marked activation of microglia and a significant loss of Purkinje cells in the vermis by 7 days postinjury. These findings emphasize the vulnerability of the cerebellum to midline traumatic brain injury.