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Related Experiment Videos

Is intertwin birth weight discordance predictable?

I Blickstein1, M Manor, R Levi

  • 1Department of Obstetrics and Gynecology, Kaplan Hospital, Rehovot, Israel.

Gynecologic and Obstetric Investigation
|January 1, 1996
PubMed
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Intertwin abdominal circumference (AC) difference and estimated fetal weight (EFW) difference show similar efficacy in predicting birth weight discordance in twins. However, neither method accurately predicts discordance due to low positive predictive values.

Area of Science:

  • Maternal-Fetal Medicine
  • Twin Gestation Research
  • Diagnostic Accuracy Studies

Background:

  • Birth weight discordance in twins poses risks to fetal well-being.
  • Accurate prediction of discordant growth is crucial for timely intervention.
  • Current predictive methods require further evaluation for efficacy.

Purpose of the Study:

  • To compare the predictive accuracy of intertwin abdominal circumference (AC) difference versus estimated fetal weight (EFW) difference for birth weight discordance.
  • To assess the efficacies of these sonographic parameters in identifying discordant fetal growth in twin pregnancies.

Main Methods:

  • Sonographic measurements of AC and femur length were obtained within two weeks of delivery in 90 twin pairs.
  • Estimated fetal weight (EFW) was calculated using Hadlock's formula.

Related Experiment Videos

  • Bayes' theorem and Mantel-Haenszel chi-squared test analyzed prediction rates for 15%, 20%, and 25% intertwin birth weight discordance using AC difference (≥18 mm) and EFW difference.

    • Main Results:

    • No significant difference was found between AC difference and EFW difference in predicting birth weight discordance at 15-25% (p=0.254) and >25% (p=0.112).
    • Both methods demonstrated similar negative predictive values for excluding discordant growth.

    Conclusions:

    • Intertwin AC difference (≥18 mm) and intertwin EFW difference exhibit comparable efficacy in ruling out discordant fetal growth.
    • Due to limited positive predictive values, neither method can reliably predict birth weight discordance in twin gestations.