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Imaging of liposomes by scanning tunneling microscopy
M H Zareie1, A Borucu, M Y Ozden
1Department of Chemical Engineering, Hacettepe University, Ankara, Turkey.
Artificial Cells, Blood Substitutes, and Immobilization Biotechnology
|September 1, 1996
Abstract:
In this study, unilamellar and multilamellar liposomes consisting of dipalmitoylphosphatidylcholine, cholesterol and dicetylphosphate were prepared. Scanning tunneling microscopy images of these liposomes on highly oriented pyrolytic graphite surfaces were obtained. It was observed that scanning tunnelling microscopy can be successfully used for high-resolution, three-dimensional structure analysis of liposomes under very mild conditions.