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[Inaugural acute cholestasis of Kawasaki disease]
A Desgripes1, P Blanc, D Debray
1Service de pédiatrie, CHI de Poissy, France.
Background:
Hepatic dysfunction with mild obstructive jaundice occurs occasionally in Kawasaki disease. Acute episode of cholestasis as a presenting symptom has never been reported.
Case Report:
A 14 year-old-boy was admitted with fever and cholestasis. He subsequently developed the classical manifestations of Kawasaki disease. No signs of liver cell injury or hepatic failure were present. Bacteriological cultures and seroimmunologic markers for viral infection remained negative. There was no ultrasonic abnormality of bile ducts. The child was given intravenous gamma globulins and salicylate. The outcome was favourable without any cardiovascular complications.
Conclusion:
A persistent febrile cholestasis of unknown etiology should evoke the diagnosis of Kawasaki disease.