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Updated: Aug 19, 2026

Construction and Systematical Symmetric Studies of a Series of Supramolecular Clusters with Binary or Ternary Ammonium Triphenylacetates
Published on: February 15, 2016
Trichoverroid stereoisomers
B B Jarvis1, S Wang, H L Ammon
1Department of Chemistry and Biochemistry, University of Maryland, College Park 20742, USA.
Abstract:
Trichoverroids, which lie along the biosynthetic path between the simple and the macrocyclic trichothecenes, have been characterized previously as sets of diastereomers that have the S-configuration at C-6' and are epimeric at C-7'. An isolate of Myrothecium verrucaria (ATCC 20540), which is the only species of Myrothecium reported to produce the macrocyclic trichothecene isororidin E (3a), produces trichoverrols (1) and trichoverrins (2) that are epimeric at C-7' but that have R-configurations at the C-6' centers. Also reported are several additional naturally occurring C6'R-series trichoverroids that have varied structural modifications, including several E,Z-isomers 7-9, 9 beta,10 beta-epoxides 11a and b, 12,13-deoxyisotrichoverrin B (10), and 8 alpha-hydroxyisotrichoverrin A (12).
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Stereoisomerism
Isomers are different chemical species that have the same chemical formula.
Transition metal complexes often exist as geometric isomers, in which the same atoms are connected through the same types of bonds but with differences in their orientation in space. Coordination complexes with two different ligands in the cis and trans positions from a ligand of interest form isomers. For example, the octahedral [Co(NH3)4Cl2]+ ion has two isomers (Figure 1) In the cis...
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