Related Experiment Video
Updated: Aug 9, 2026
12:02
Isolation and Culture of Endothelial Cells from the Embryonic Forebrain
Published on: January 23, 2014
Platelet/endothelial cell adhesion molecule-1 (PECAM-1) expression by human brain microvessel endothelial cells in
1Department of pathology and Laboratory Medicine, Vancouver Hospital, Canada.
Brain Research
|August 26, 1996
Abstract:
PECAM-1 expression was investigated in primary cultures of human brain microvessel endothelial cells (HBMEC). HBMEC constitutively express PECAM-1 along their apical cell surface, advancing processes and on the basal surface at points of contact with the extracellular matrix. Surface expression is not altered by cytokine or lipopolysaccharide treatment. This distribution may mediate cell-cell contract and migration during angiogenesis and HBMEC-leukocyte interactions in CNS inflammation.
