Insights into the electrophysiology of accessory pathway-mediated arrhythmias provided by the catheter ablation...

The success of catheter ablation has greatly improved the care of patients with paroxysmal tachycardias and has caused a revolution in the practice of electrophysiology. Some investigators have expressed that concern over procedural success in an increasingly interventional specialty threatens to eclipse attempts to understand the physiology of arrhythmia syndromes. Alternatively, due to the precise and directed nature of the lesions created with radiofrequency energy, catheter ablation procedures have allowed investigation to continue at a more focused level. In this article, the insights provided by the catheter ablation experience into the physiology of arrhythmias mediated by accessory AV pathways will be reviewed. Although the learning process was sometimes delayed by the nearly immediate success of radiofrequency catheter ablation, difficult situations have continued to renew efforts for understanding at a deeper level. Conscious attempts at "learning while burning" will provide the opportunity to investigate aspects of bypass tract physiology that remain incompletely characterized, such as partial response to therapy and late recurrence.