Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Paternity after unilateral cryptorchidism: a controlled study

P A Lee1, L A O'Leary, N J Songer

  • 1Department of Pediatrics, University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh, PA 15213-2583, USA.

Pediatrics
|October 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mars Extant Life: What's Next? Conference Report.

Astrobiology·2020
Same author

The amino-terminal domain of ORF149 of koi herpesvirus is preferentially targeted by IgM from carp populations surviving infection.

Archives of virology·2016
Same author

Subglacial Lake Whillans microbial biogeochemistry: a synthesis of current knowledge.

Philosophical transactions. Series A, Mathematical, physical, and engineering sciences·2015
Same author

A two-part model for reference curve estimation subject to a limit of detection.

Statistics in medicine·2011
Same author

Seasonal 25-hydroxyvitamin D changes in British postmenopausal women at 57 degrees N and 51 degrees N: a longitudinal study.

The Journal of steroid biochemistry and molecular biology·2010
Same author

Consensus statement on terminology and management: disorders of sex development.

Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation·2008

Paternity was compromised in men with a history of unilateral cryptorchidism, with infertility occurring twice as often compared to controls. Age at surgery or lifestyle did not impact paternity outcomes.

Area of Science:

  • Urology
  • Reproductive Medicine
  • Pediatric Surgery

Background:

  • Cryptorchidism, specifically unilateral cryptorchidism, is a condition affecting male reproductive health.
  • Surgical correction (orchiopexy) is performed to address undescended testes.

Purpose of the Study:

  • To investigate the long-term impact of formerly unilateral cryptorchidism on paternity.
  • To compare paternity rates between men who underwent orchiopexy and a control group.

Main Methods:

  • Retrospective review of medical records for formerly unilateral cryptorchid men treated between 1955-1971.
  • Survey questionnaires administered to both cryptorchid and control groups to assess paternity outcomes.

Main Results:

Related Experiment Videos

  • Men with a history of unilateral cryptorchidism had significantly higher rates of infertility (10.5%) compared to controls (5.4%).
  • No differences were observed in time to conception between groups.
  • Paternity was associated with female infertility factors and the presence of varicoceles in both groups.
  • Conclusions:

    • Unilateral cryptorchidism compromises paternity, leading to approximately double the rate of infertility compared to the general population.
    • Subfertility, defined by longer conception times, was not evident in the fertile subgroup.
    • The age of orchiopexy did not correlate with paternity outcomes.