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Dyslipidemia in urban Thais
V Tanphaichitr1, R Pakpeankitvatana, P Leelahagul
1Department of Medicine and Research Center, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Biomedical and Environmental Sciences : BES
|September 1, 1996
Summary
Affluent urban Thai men and women, particularly those in the Electricity Generating Authority of Thailand (EGAT), exhibit higher serum lipid levels, including total cholesterol and LDL-C. Dietary fat intake appears to influence these lipid profiles, with potential benefits observed from linoleate consumption.
Area of Science:
- Cardiovascular Health
- Nutritional Epidemiology
- Biochemistry
Background:
- Serum lipid profiles are critical indicators of cardiovascular disease risk.
- Understanding lipid variations in different population groups is essential for public health initiatives.
- Affluent urban populations may have distinct dietary patterns influencing metabolic health.
Purpose of the Study:
- To compare serum lipid profiles between EGAT officials and Ramathibodi Hospital Staff (RHS), two affluent urban Thai cohorts.
- To investigate gender-based differences in serum lipid levels within these populations.
- To explore the potential influence of dietary fat intake on serum lipid profiles and dyslipidemia prevalence.
Main Methods:
- Cross-sectional study involving 2,703 EGAT male and 792 female officials (aged 35-54) and 519 RHS staff (66 male, 453 female; aged 19-61).
- Measurement of serum total cholesterol (TC), LDL-C, HDL-C, and triglycerides (TG).
- Assessment of dietary fat intake as a percentage of daily calories.
Main Results:
- EGAT officials had significantly higher TC, LDL-C, and TG levels than RHS counterparts of the same sex, but lower HDL-C.
- Men in both groups exhibited higher TC, LDL-C, and TG, and lower HDL-C compared to women.
- Hypercholesterolemia, primarily due to elevated LDL-C, was the main dyslipidemia; RHS showed less severe LDL-C elevation and higher prevalence of protective HDL-C levels (>1.55 mmol/L).
- EGAT officials consumed a higher percentage of dietary fat (39%) compared to RHS (31%).
Conclusions:
- Dietary fat intake is a plausible influencing factor on serum lipid levels in affluent urban Thais.
- EGAT officials present a lipid profile indicative of higher cardiovascular risk compared to RHS.
- Higher intake of linoleate may confer beneficial effects on serum lipoprotein profiles, as suggested in the RHS group.