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Unlabelled:
The development of the intestine was investigated in 8-16 1/2 days' mouse embryos. Graphical and three-dimensional reconstructions were made. Special attention was paid to the appearance and the regression of the umbilical hernia. In representative stages (10, 10 1/2, 11 1/2, 12 1/2, and 14 1/2 days) the distribution of mitotic epithelial cells was studied.
Conclusions:
1. In adult mice a total of eight intestinal loops is observed. Their development occurred before the age of 16 1/2 foetal days. 2. A correlation between the numbers and locations of mitoses on the one hand and the intestinal configurations on the other was established. 3. The presence of an umbilical hernia could not be confirmed after the age of 16 1/2 foetal days. 4. Both the differentiating and the adult intestinal tract, except the duodenum, do not show a regular pattern of intrinsic of extrinsic topographic relations.