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Pneumococcal meningitis in children

R M Laxer, M I Marks

    American Journal of Diseases of Children (1960)
    |August 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Pneumococcal meningitis in children often leads to severe outcomes and neurological issues, particularly in infants. While mortality has decreased, prompt diagnosis and treatment remain critical for improving prognosis in pediatric cases.

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    Area of Science:

    • Pediatrics
    • Infectious Diseases
    • Neurology

    Background:

    • Pneumococcal meningitis is a serious infection in children.
    • Understanding its clinical and laboratory features is crucial for prognosis.

    Purpose of the Study:

    • To review the clinical and laboratory features of pneumococcal meningitis in children.
    • To analyze factors associated with mortality and neurological sequelae.

    Main Methods:

    • Retrospective review of 79 children with 83 episodes of pneumococcal meningitis over 26 years.
    • Analysis of clinical presentation, laboratory findings, treatment, and outcomes.

    Main Results:

    • 31% of patients experienced convulsions; mortality was 10.8%, primarily in infants under 1 year.

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  • Poor prognostic indicators included pneumonia, hypoglycorrhachia, and elevated CSF protein.
  • 56% of patients had neurological sequelae, such as deafness and hydrocephalus.

    • Conclusions:

    • Pneumococcal meningitis in children, despite reduced mortality, is frequently associated with severe outcomes.
    • Early identification of poor prognostic factors is essential for managing pediatric pneumococcal meningitis.