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Related Experiment Videos

Spiculated axillary adenopathy

D D Dershaw1, D G Selland, L K Tan

  • 1Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

Radiology
|November 1, 1996
PubMed
Summary
This summary is machine-generated.

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Imaging and the completion of the omics paradigm in breast cancer.

Der Radiologe·2018

Spiculated axillary lymph nodes on mammograms indicate extranodal tumor extension in breast cancer patients. This imaging finding suggests aggressive disease and a poorer prognosis, aiding in patient management.

Area of Science:

  • Radiology
  • Oncology
  • Pathology

Background:

  • Axillary lymph node status is critical in breast cancer staging.
  • Imaging plays a key role in detecting nodal involvement.

Purpose of the Study:

  • To characterize the mammographic and sonographic appearance of spiculated axillary lymph nodes.
  • To correlate imaging findings with histopathology and patient outcomes.

Main Methods:

  • Prospective identification of 11 cases with spiculated axillary nodes on mammograms.
  • Review of medical records, including mammography, sonography, and histopathology.
  • Correlation of imaging findings with nodal histopathology and patient outcomes.

Main Results:

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  • All patients had primary invasive breast carcinoma.
  • Spiculated nodes correlated with extranodal tumor extension into perinodal fat.
  • Nodes appeared iso- to hyperdense on mammograms and hypoechoic with irregular margins on sonograms.
  • Conclusions:

    • Spiculated axillary adenopathy suggests extranodal extension of breast cancer.
    • This finding indicates a biologically aggressive tumor with a potentially poor prognosis.
    • Imaging detection of spiculated nodes can inform treatment strategies.