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Published on: November 21, 2017
Selective cerebral hypothermia by means of transfemoral internal carotid artery catheterization
A E Schwartz1, J G Stone, J Pile-Spellman
1Department of Anesthesiology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.
Abstract:
Global cerebral hypothermia of 24 degrees C was induced without systemic cooling by means of selective hypothermic perfusion of a single internal carotid artery in four baboons. With a closed-circuit pump system, blood was withdrawn from the femoral artery, cooled in a water bath, and infused through an internal carotid artery catheter, which was positioned with fluoroscopic guidance. This endovascular technique may have applications in the treatment of neurologic disease in humans.
