Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Endoscopic laser therapy for watermelon stomach

M J Bourke1, R L Hope, P Boyd

  • 1Department of Gastroenterology, Westmead Hospital, Sydney, New South Wales, Australia.

Journal of Gastroenterology and Hepatology
|September 1, 1996
PubMed
Summary

Neodymium:yttrium-aluminium-garnet laser coagulation effectively treats gastric antral vascular ectasia (watermelon stomach), resolving anemia caused by gastrointestinal bleeding. This safe therapy significantly reduces transfusion needs and improves hemoglobin levels.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Immunoglobulin G subclass 4-related colonic submucosal lesion.

Gastrointestinal endoscopy·2025
Same author

Cardiac tamponade arising from a venous source following anterograde dissection re-entry coronary angioplasty to a chronic total occlusion.

Cardiovascular intervention and therapeutics·2015
Same author

Association of Synergistetes and Cyclodipeptides with Periodontitis.

Journal of dental research·2015
Same author

A prolonged outbreak of invasive meningococcal disease in an extended Irish Traveller family across three Health Service Executive (HSE) areas in Ireland, 2010 to 2013.

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin·2015
Same author

Patient evaluation of outpatient venous thromboembolism prophylaxis service following lower limb injuries using a developed validated questionnaire.

Journal of perioperative practice·2015
Same author

An experimental and computational study of the hydrodynamics of high-velocity water microdrops for interproximal tooth cleaning.

Journal of the mechanical behavior of biomedical materials·2015

Area of Science:

  • Gastroenterology
  • Hematology
  • Medical Technology

Background:

  • Gastric antral vascular ectasia (GAVE), also known as watermelon stomach, is a condition causing significant gastrointestinal blood loss.
  • Anemia resulting from GAVE often necessitates frequent blood transfusions, impacting patient quality of life.

Purpose of the Study:

  • To evaluate the efficacy and safety of neodymium:yttrium-aluminium-garnet (Nd:YAG) laser coagulation for treating anemia secondary to GAVE.
  • To assess the impact of Nd:YAG laser treatment on transfusion requirements and hemoglobin levels in patients with GAVE.

Main Methods:

  • A cohort of eleven patients with anemia due to GAVE underwent Nd:YAG laser coagulation therapy.
  • Treatment involved a median of 3.0 sessions, with outcomes assessed over a mean follow-up period of 27.3 months.

Related Experiment Videos

Main Results:

  • Nd:YAG laser coagulation led to a significant reduction in transfusion requirements, from 2.5 units/month pre-treatment to 0.4 units/month post-treatment (P < 0.02).
  • Mean hemoglobin levels improved significantly from 7.7 g/dL to 11.9 g/dL (P < 0.001).
  • Six patients became transfusion-independent, and two experienced minimal transfusion needs post-treatment.

Conclusions:

  • Nd:YAG laser coagulation is a safe and effective first-line therapy for managing anemia associated with GAVE.
  • The procedure demonstrates substantial clinical benefit by reducing transfusion dependency and improving hematological parameters.