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Colonic transit time in constipated children: does pediatric slow-transit constipation exist?
M A Benninga1, H A Büller, G N Tytgat
1Department of Pediatrics, University Hospital, Utrecht.
Journal of Pediatric Gastroenterology and Nutrition
|October 1, 1996
Summary
This study identifies pediatric slow-transit constipation (PSTC) in children using colonic transit time measurements. Key clinical indicators for PSTC include nighttime soiling and palpable rectal masses.
Area of Science:
- Pediatric Gastroenterology
- Colorectal Surgery
- Functional Gastrointestinal Disorders
Background:
- Slow-transit constipation (STC) is recognized in adults but not well-defined in children.
- Constipated children often present with complex symptoms requiring diagnostic clarification.
Purpose of the Study:
- To investigate the existence and characteristics of pediatric slow-transit constipation (PSTC).
- To correlate objective transit measurements with clinical presentations in constipated children.
Main Methods:
- Prospective study of 94 constipated children (median age 8.0 years).
- Colonic transit time (CTT) measured using radioopaque markers.
- Orocecal transit time, anorectal manometry, and behavioral assessments were also performed.
Main Results:
- Pediatric slow-transit constipation (CTT > 100 hours) identified in 24% of patients.
- PSTC group showed significantly prolonged total and segmental CTTs compared to normal/delayed transit constipation (NDTC).
- Nighttime soiling and palpable rectal masses were significant clinical indicators for PSTC.
Conclusions:
- Objective evidence supports the existence of pediatric slow-transit constipation.
- Clinical features like nighttime soiling and palpable rectal masses aid in recognizing PSTC.
- Further research is needed to understand PSTC mechanisms and optimal treatment strategies.