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[Hb, C, D and E hemoglobinopathies]
1Department of Clinical Laboratory Science, Yamaguchi University School of Medicine.
Nihon Rinsho. Japanese Journal of Clinical Medicine
|September 1, 1996
Insights
The four common hemoglobin variants (Hb C, D, E, S) are rare in Japanese populations but may be seen in recent immigrants. This review covers their distribution, symptoms, and diagnosis.
Area of Science:
- Hematology
- Genetics
Abstract:
The four commonest beta chain variants of human hemoglobin (Hb), i.e. Hbs C, D, E, and S were absent or quite infrequent in Japanese. They are occasionally found in visitors and immigrants to Japan recently. Geographical distribution, clinical expression, pathophysiology and diagnosis of Hbs C, D and E are briefly reviewed.