Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Hemolytic anemias observed in SLE]

Y Ichikawa1, C Tanaka, N Ohya

  • 1St. Marianna University School of Medicine, Institute of Medical Science.

Nihon Rinsho. Japanese Journal of Clinical Medicine
|September 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effects of an exercise program on muscle performance in patients undergoing allogeneic bone marrow transplantation.

Bone marrow transplantation·2003
Same author

Clinical manifestations and course of 200 Japanese patients with Behçet's disease.

Advances in experimental medicine and biology·2003
Same author

Soluble Fas ligand levels in cerebrospinal fluid in neuro-Behçet's disease.

Advances in experimental medicine and biology·2003
Same author

Expression of an inhibitor of apoptosis, survivin, in oral carcinogenesis.

Journal of dental research·2003
Same author

Usefulness of automatic detection of fragmented red cells using a hematology analyzer for diagnosis of thrombotic microangiopathy.

Clinical and laboratory haematology·2002
Same author

A GPVI polymorphism is a risk factor for myocardial infarction in Japanese.

Atherosclerosis·2002

Systemic lupus erythematosus (SLE) patients can experience hemolytic anemia, including autoimmune hemolytic anemia (AIHA) and thrombotic microangiopathic hemolytic anemia (TMHA). TMHA requires consideration in SLE exacerbations due to overlapping symptoms.

Area of Science:

  • Hematology
  • Immunology
  • Rheumatology

Context:

  • Systemic lupus erythematosus (SLE) is associated with hemolytic anemia.
  • Two main types of hemolytic anemia in SLE are autoimmune hemolytic anemia (AIHA) and thrombotic microangiopathic hemolytic anemia (TMHA).
  • AIHA involves anti-erythrocyte antibodies, detectable by direct Coombs' test, with anti-phospholipid antibodies emerging as a potential cause.

Purpose:

  • To differentiate between AIHA and TMHA in SLE patients.
  • To highlight the clinical similarities between TMHA and SLE exacerbations.
  • To emphasize the importance of considering TMHA in the differential diagnosis of acute SLE flares.

Summary:

  • Hemolytic anemia in SLE encompasses AIHA and TMHA.
  • TMHA presents with fever, hemolytic anemia, thrombocytopenia, central nervous system symptoms, and renal insufficiency.

Related Experiment Videos

  • Clinical manifestations of TMHA significantly overlap with SLE itself, necessitating its consideration during acute exacerbations.

    • Impact:

    • Improved diagnostic accuracy for hemolytic anemia in SLE patients.
    • Facilitates timely and appropriate management of TMHA in the context of SLE.
    • Enhances understanding of the complex interplay between hematologic disorders and autoimmune diseases like SLE.