[Enflurane anaesthesia for epileptic patients (author's transl)]
Related Experiment Video
Updated: Oct 16, 2026

In Vitro Method to Control Concentrations of Halogenated Gases in Cultured Alveolar Epithelial Cells
Published on: October 23, 2018
Insights
Enflurane anesthesia did not provoke seizures in patients with a history of cerebral convulsions. This study suggests that a history of seizures is not a contraindication for using enflurane during surgery.
Area of Science:
- Anesthesiology
- Neurology
Abstract:
Enflurane anaesthesia with continuous EEG-registration was given to 21 patients, aged 3 to 53 years, who had a history of cerebral convulsions. 11 patients were children up to the age of 14 years. There was no obvious changes or correlation between enflurane concentration and intraoperative EEG-findings. The registered cramp potentials were the same as those registered preceeding the operations. Provocation as a result of the enflurane anaesthesia was not observed in any patient. The anticonvulsive basic treatment preceeding the operations made the interpretation of our results difficult. The warning by some authors against the use of Enflurane anaesthesia in patients with a history of cerebral convulsions could not be confirmed. Therefore, we conclude that a history of cerebral convulsions is not a general contraindication for the use of enflurane.
More Related Videos
09:36Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device
Published on: September 24, 2020
03:02Application of Dixon's Up-and-Down Design to Estimate the Minimum Alveolar Concentration of Sevoflurane in Rats with Refined Movement Classification
Published on: July 25, 2025
Related Concept Videos
Local Anesthetics: Clinical Application as Epidural Anesthesia
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
General Anesthesia: Overview
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
Parenteral Anesthetics: Overview
Inhalational Anesthetics: Overview
Epilepsy and Seizures: Overview
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Drug Delivery: Enteral Route
Drugs in...