The epidemiology of lung cancer: review of risk factors and Spanish data

Lung cancer is the main form of cancer among men both in Spain and in the rest of europe. However, Spanish incidence rates are among the lowest of the European registries, especially for women. In this country, lung cancer mortality increased much more rapidly for men than for women between the fifties and the eighties. This increase was larger for lung cancer than for any other site. The trend of incidence, in Spain as well as in the greatest part of the world, is entirely explained by tobacco consumption, which remains the major risk factor for lung cancer. Occupational radon and asbestos exposures are other important but less extended determinants of lung cancer. Genetic factors could also play a role in the occurrence of the disease. On the other side, a high consumption of fruit and vegetables is protective, but, so far, no single dietary component has been found to be preventive. In this article, we review the major risk factors of lung cancer with an emphasis on Spanish and European data.