Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Predicting empty follicle syndrome

G Ndukwe1, S Thornton, S Fishel

  • 1Nottingham University Research and Treatment Unit in Reproduction (NURTURE), Department of Obstetrics and Gynaecology, Queen's Medical Centre, United Kingdom.

Fertility and Sterility
|November 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Identification of Conduction Velocity of Bladder Afferent and Efferent Signals in the Sacral Roots of Sheep Using Cross-Correlation Methods.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
Same author

Fermi surface and pseudogap in highly doped Sr<sub>2</sub>IrO<sub>4</sub>.

npj quantum materials·2025
Same author

Nature of Metallic and Insulating Domains in the Charge-Density-Wave System 1T-TaSe_{2}.

Physical review letters·2025
Same author

Reach-back to subject matter experts improves healthcare quality, influences the decision to evacuate and reduces costs: an observational study of the UK Defence Medical Services Deployed Telemedicine System.

BMJ military health·2025
Same author

Dermal wipe sampling method development and validation for semivolatile and nonvolatile flame-retardant compounds TBBPA and TPP for use in occupational exposure assessments.

Journal of occupational and environmental hygiene·2025
Same author

Health-related quality of life in cutaneous T-cell lymphoma: A post hoc analysis of a phase 3 trial in mycosis fungoides and Sézary syndrome.

Journal of the European Academy of Dermatology and Venereology : JEADV·2024
Same journal

Confronting complexities of uterus transplantation: Balancing Innovation, Risk and Access.

Fertility and sterility·2026
Same journal

Fertility Benefits and Parental Leave Policies across Accreditation Council for Graduate Medical Education (ACGME) Programs with Ob/Gyn Residency Programs.

Fertility and sterility·2026
Same journal

Optimizing the therapeutic donor insemination cycle.

Fertility and sterility·2026
Same journal

Hormonal and metabolic effects of the administration of oral low-dose 17-β-estradiol (0.2 mg) in patients with Functional Hypothalamic Amenorrhea (FHA): A Retrospective Pilot Study.

Fertility and sterility·2026
Same journal

Biomarker or Bystander? Considering Triglyceride Glucose-Body Mass Index (TyG-BMI) in Patients with Polyendocrine Metabolic Ovarian Syndrome.

Fertility and sterility·2026
Same journal

The Importance of the Incubator: Perinatal Outcomes following Intravaginal Culture.

Fertility and sterility·2026
See all related articles

A simple test can predict empty follicle syndrome before oocyte retrieval. Measuring serum beta-human chorionic gonadotropin (beta-hCG) 36 hours after administration can identify patients at risk for this condition.

Area of Science:

  • Reproductive Endocrinology
  • Assisted Reproductive Technologies (ART)
  • Clinical Diagnostics

Background:

  • Empty follicle syndrome (EFS) is a challenging complication in assisted reproductive technologies.
  • Predicting EFS before oocyte retrieval is crucial for optimizing treatment protocols and patient counseling.

Purpose of the Study:

  • To identify a simple and reliable predictive test for empty follicle syndrome (EFS).
  • To evaluate the utility of serum beta-human chorionic gonadotropin (beta-hCG) levels as a predictor of EFS.

Main Methods:

  • Retrospective analysis of patients undergoing superovulation for ART.
  • Comparison of serum beta-hCG levels 36 hours post-hCG administration between women with and without EFS.
  • Ultrasound monitoring of follicular growth and serum estradiol (E2) levels were also assessed.

Related Experiment Videos

Main Results:

  • Women with EFS exhibited significantly lower serum beta-hCG levels (4 +/- 1.8 mIU/mL) 36 hours after hCG administration compared to women with successful oocyte retrieval (209 +/- 16.7 mIU/mL).
  • Pre-hCG administration beta-hCG levels were undetectable in both groups.

Conclusions:

  • Low serum beta-hCG bioavailability is associated with empty follicle syndrome.
  • Measuring serum beta-hCG levels 36 hours after intramuscular hCG administration serves as a simple predictive test for EFS.