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Subregional mapping of the human lymphocyte prolyl oligopeptidase gene (PREP) to human chromosome 6q22
F J Goossens1, J G Wauters, G C Vanhoof
1Department of Clinical Biochemistry, University of Antwerp, Wilrijk, Belgium.
Cytogenetics and Cell Genetics
|January 1, 1996
Abstract:
Prolyl oligopeptidase is a large monomeric proline specific serine endopeptidase, the activity of which correlates well with different stages of depression. We have subregionally mapped human lymphocytic prolyl oligopeptidase (PREP) by FISH using a cosmid probe. The probe mapped to the long arm of chromosome 6, and the signal clustered in band q22.