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Management of resistant depression
1Department of Psychiatry, University of Alberta.
Canadian Family Physician Medecin De Famille Canadien
|October 1, 1996
Abstract:
Treatment-resistant depression is a relative concept. It has been formally defined as a mood disorder that fails to respond to three adequate trials of antidepressants. However, treatment resistance is relative to the expertise and knowledge of the treating physician and the availability of resources, such as electroconvulsive therapy. Only about 7% of patients show absolute treatment resistance, and even they can be helped.