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Blastocystis hominis revisited
1Analytical Electron Microscopy Facility, Queensland University of Technology, Australia.
Clinical Microbiology Reviews
|October 1, 1996
Summary
Blastocystis hominis, a common intestinal parasite, remains poorly understood regarding its biology, taxonomy, and pathogenicity. Further research is needed to clarify its life cycle, transmission, and effective treatment strategies.
Area of Science:
- Microbiology
- Parasitology
- Gastroenterology
Background:
- Blastocystis hominis is a common unicellular organism in human and animal intestines.
- Its basic biology, taxonomy, and pathogenicity are poorly understood.
- Multiple morphological forms exist, including newly identified cyst and multivacuolar forms.
Purpose of the Study:
- To highlight the knowledge gaps in Blastocystis hominis biology.
- To discuss the controversies surrounding its taxonomy and pathogenicity.
- To review diagnostic methods and treatment options.
Main Methods:
- Literature review of existing studies on Blastocystis hominis.
- Analysis of morphological characteristics and diagnostic approaches.
- Discussion of proposed life cycles and treatment failures.
Main Results:
- Blastocystis hominis exhibits diverse morphological forms, complicating identification.
- Its life cycle and transmission routes are not experimentally validated.
- Metronidazole is the suggested treatment, but eradication failures are reported.
Conclusions:
- Significant gaps exist in understanding Blastocystis hominis basic biology.
- Accurate diagnosis may require identifying less common morphological forms.
- Further research is crucial for effective management and treatment of Blastocystis hominis infections.