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Guillain-Barré syndrome with hydrocephalus in early infancy
Insights
Guillain-Barré syndrome (GBS) can affect infants, presenting as a floppy infant. High cerebrospinal fluid protein levels in infants with GBS may indicate concurrent hydrocephalus.
Area of Science:
- Neurology
- Pediatrics
- Clinical Case Reports
Background:
- Guillain-Barré syndrome (GBS) is a rare acquired neurologic disorder typically seen in childhood.
- GBS is often overlooked in infants, not commonly considered in the differential diagnosis of a floppy infant.
Abstract:
Guillain-Barré syndrome (GBS) is a self-limited and uncommon acquired neurologic syndrome in childhood. It is not thought of as a problem of infancy and is not always included in the differential diagnosis of the floppy infant. This case report describes GBS ina 1-month-old infant. In addition this infant developed hydrocephalus concurrent with the appareance of high CSF protein levels. This patient is described to demonstrate that GBS can occur at all ages and that hydrocephalus may occur particularly when the CSF protein is at an unusually high level.