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Erythema elevatum diutinum, cryoglobulinaemia, and fixed urticaria on cooling
The British Journal of Dermatology
|July 1, 1977
Abstract:
A mixed cryoglobulin (IgG/IgM) was detected in a patient with erythema elevatum diutinum. Cold exposure activated the complement system and provoked a fixed urticarial reaction with the histology of a leukocytoclastic vasculitis.