Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Does fluoridation harm immune function?

S J Challacombe1

  • 1Department of Oral Medicine and Pathology, UMDS, Guy's Hospital, London, UK.

Community Dental Health
|September 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Caries clusters at lesion-severity thresholds: A Sierra Leone case study.

Community dentistry and oral epidemiology·2023
Same author

Unmet need in Sierra Leone: a national oral health survey of schoolchildren.

BDJ open·2022
Same author

Virucidal activity.

British dental journal·2020
Same author

Povidone iodine.

British dental journal·2020
Same author

Validation of an Oral Disease Severity Score (ODSS) tool for use in oral mucous membrane pemphigoid.

The British journal of dermatology·2019
Same author

Is the Oral Disease Severity Score going to be useful for dermatologists when assessing pemphigus? Reply from the authors.

The British journal of dermatology·2018
Same journal

School - based oral health promotion strategies: A global scoping review.

Community dental health·2026
Same journal

The primordial policy gap in dental caries control in Iran: From national DMFT success to the persistent challenge of the significant caries index (SIC): Policy brief.

Community dental health·2026
Same journal

Oral pain among young adolescents in Tanzania: A cross-sectional study.

Community dental health·2026
Same journal

Biosafety practices in Brazilian dentistry after the COVID-19 public health emergency: Persistence and discontinuation of protective measures.

Community dental health·2026
Same journal

Tobacco use and its impact on oral health among female adolescents in Riyadh, Saudi Arabia.

Community dental health·2026
Same journal

Associations between ethnicity, socioeconomic status and dental caries in children: A population-based record linkage longitudinal cohort study.

Community dental health·2026
See all related articles

Fluoridation does not harm immune function, despite public concerns. Studies show that fluoride, even at high doses, does not negatively impact specific immunity or cause allergic reactions.

Area of Science:

  • Immunology
  • Public Health
  • Toxicology

Background:

  • Public concerns exist regarding the potential impact of water fluoridation on the immune system.
  • Previous research has explored the relationship between fluoride exposure and immune responses.

Purpose of the Study:

  • To critically evaluate the scientific evidence concerning the effects of fluoridation on human immunity.
  • To address public misconceptions about fluoride and immune function.

Main Methods:

  • Review and analysis of existing scientific literature on fluoride and immune function.
  • Examination of studies investigating the effects of fluoride on lymphocytes and polymorphonuclear leucocytes.
  • Assessment of data on fluoride's role as an immunological adjuvant.

Related Experiment Videos

Main Results:

  • Current scientific evidence does not support the suggestion that fluoridation negatively affects immunity.
  • High concentrations of fluoride, far exceeding those from fluoridation, can inhibit certain immune cell functions.
  • Fluoride has demonstrated potential as an immunological adjuvant.
  • No evidence of detrimental effects on specific immunity or confirmed allergic reactions linked to fluoridation.

Conclusions:

  • Water fluoridation at recommended levels is not associated with adverse effects on the immune system.
  • The concentrations of fluoride required to impact immune function are significantly higher than those typically encountered through fluoridation.
  • Further research confirms the safety of fluoridation regarding immunological health.