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Updated: Aug 7, 2026

Analysis of mRNA Nuclear Export Kinetics in Mammalian Cells by Microinjection
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Analysis of mRNA Nuclear Export Kinetics in Mammalian Cells by Microinjection

Published on: December 4, 2010

Export of ribosomal subunits from resealed rat liver nuclear envelopes

I Hassel1, V Cézanne, C Treviño

  • 1Institut für Biochemie der Johann Wolfgang Goethe-Universität Frankfurt, Germany.

European Journal of Biochemistry
|October 1, 1996
PubMed

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Before mRNAs are exported to the cytoplasm, it is crucial to check each mRNA for structural and functional integrity. Eukaryotic cells use several different mechanisms, collectively known as mRNA surveillance, to look for irregularities in mRNAs. Irregular or aberrant mRNA are rapidly degraded by various enzymes. If a defective mRNA escapes the surveillance, it would be translated into a protein which would either be non-functional or not function properly. One of the primary irregularities in...
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