Local anesthetic molecules transiently block currents through individual open acetylcholine receptor channels [proceedings]

The neurosteroid 5β-pregnan-3α-ol-20-one enhances actions of etomidate as a positive allosteric modulator of α1β2γ2L GABAA receptors.

British journal of pharmacology·2014

Developmental changes in acetylcholine receptor aggregates at rat skeletal neuromuscular junctions.

Developmental biology·2010

Structurally diverse amphiphiles exhibit biphasic modulation of GABAA receptors: similarities and differences with neurosteroid actions.

British journal of pharmacology·2010

Actions of anesthetics on excitatory transmitter-gated channels.

Handbook of experimental pharmacology·2008

Mechanisms of potentiation of the mammalian GABAA receptor by the marine cembranoid eupalmerin acetate.

British journal of pharmacology·2007

Physicochemical and physiological properties of 5alpha-cyprinol sulfate, the toxic bile salt of cyprinid fish.

Journal of lipid research·2003

Spatiotemporal 4D Whole-cell Modeling of a Minimal Autotroph Reveals Central Carbon Metabolism Regulated Locally by Protein Megacomplexes via Post-translational Modifications under Light Disturbance.

Biophysical journal·2026

Conformational ensembles of flexible multidomain proteins: How close are we to accurate and reliable predictions?

Biophysical journal·2026

Constant-pH molecular dynamics simulations of closed and open states of a proton-gated ion channel.

Biophysical journal·2026

Single-Molecule Force Spectroscopy Reveals a High-Force Requirement for Dissociation of Integrin Transmembrane Domains.

Biophysical journal·2026

The transmembrane domain regulates the kinetics of the SARS-CoV-2 spike conformational transition.

Biophysical journal·2026

The isolated Stachel peptide of the adhesion G protein-coupled receptor ADGRG6 is predominantly disordered with local helical propensity.

Biophysical journal·2026

Profiling of euphane and tirucallane triterpenes from Euphorbia systyloides on antichagasic activity reveals antileukemia and immunomodulatory effects.

Pharmaceutical biology·2026

Second-generation H1 antihistamines for the treatment of chronic urticaria: a network meta-analysis.

Frontiers in medicine·2026

Carbon dots derived from natural medicines: Therapeutic advances and challenges.

Journal of pharmaceutical analysis·2026

A Dual-Halogen Labeling Strategy to Detect and Quantify Double-Stranded RNAs Using NanoSIMS: A Proof-of-Concept Study.

ACS omega·2026

Design, Synthesis, and Dft Analysis of Benzaldehyde-Based Ethynyl-Functionalized Donor-Acceptor Dicyanomethyl Derivatives.

ACS omega·2026

Anti-hypoxic activity of Biyang floral mushroom polyphenols: deep eutectic solvent-based ultrasound-assisted extraction versus ethanol extraction.

Food science and biotechnology·2026

Related Experiment Videos

Local anesthetic molecules transiently block currents through individual open acetylcholine receptor channels

Related Concept Videos

The neurosteroid 5β-pregnan-3α-ol-20-one enhances actions of etomidate as a positive allosteric modulator of α1β2γ2L GABAA receptors.

Developmental changes in acetylcholine receptor aggregates at rat skeletal neuromuscular junctions.

Structurally diverse amphiphiles exhibit biphasic modulation of GABAA receptors: similarities and differences with neurosteroid actions.

Actions of anesthetics on excitatory transmitter-gated channels.

Mechanisms of potentiation of the mammalian GABAA receptor by the marine cembranoid eupalmerin acetate.

Physicochemical and physiological properties of 5alpha-cyprinol sulfate, the toxic bile salt of cyprinid fish.

Spatiotemporal 4D Whole-cell Modeling of a Minimal Autotroph Reveals Central Carbon Metabolism Regulated Locally by Protein Megacomplexes via Post-translational Modifications under Light Disturbance.

Conformational ensembles of flexible multidomain proteins: How close are we to accurate and reliable predictions?

Constant-pH molecular dynamics simulations of closed and open states of a proton-gated ion channel.

Single-Molecule Force Spectroscopy Reveals a High-Force Requirement for Dissociation of Integrin Transmembrane Domains.

The transmembrane domain regulates the kinetics of the SARS-CoV-2 spike conformational transition.

The isolated Stachel peptide of the adhesion G protein-coupled receptor ADGRG6 is predominantly disordered with local helical propensity.

Profiling of euphane and tirucallane triterpenes from Euphorbia systyloides on antichagasic activity reveals antileukemia and immunomodulatory effects.

Second-generation H1 antihistamines for the treatment of chronic urticaria: a network meta-analysis.

Carbon dots derived from natural medicines: Therapeutic advances and challenges.

A Dual-Halogen Labeling Strategy to Detect and Quantify Double-Stranded RNAs Using NanoSIMS: A Proof-of-Concept Study.

Design, Synthesis, and Dft Analysis of Benzaldehyde-Based Ethynyl-Functionalized Donor-Acceptor Dicyanomethyl Derivatives.

Anti-hypoxic activity of Biyang floral mushroom polyphenols: deep eutectic solvent-based ultrasound-assisted extraction versus ethanol extraction.

Related Experiment Videos

Local anesthetic molecules transiently block currents through individual open acetylcholine receptor channels...

Related Concept Videos

Related Articles

Local anesthetic molecules transiently block currents through individual open acetylcholine receptor channels