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Limitations of diazomethane for the quantification of 15-oxo-prostaglandin F2alpha
Biomedical Mass Spectrometry
|June 1, 1977
Abstract:
The relatively rapid formation of pyrazoline adducts is a serious side reaction in the esterification of 15-oxo-PGF2alpha with ethereal diazomethane under conditions used routinely in the chemical derivatization of prostaglandins.