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Antigen Ki-67 and c-myc oncogene as related to histoclinical parameters in pigmented skin lesions
M Korabiowska1, U Brinck, J Mirecka
1Department of Pathology, Georg-August University Göttingen, Germany.
In Vivo (Athens, Greece)
|September 1, 1995
Abstract:
121 cases of cutaneous melanomas, 82 lymph nodes with melanoma metastases and 62 naevi were stained immunohistochemically for presence of Ki-67 antigen and c-myc oncogene. A significant correlation between expression of investigated markers, and survival time as well as presence of metastases, in cutaneous melanomas was found (p < 0.05). The role of Ki-67 antigen for differential diagnosis between naevi and melanomas is also demonstrated.