[Premedication with midazolam in adults with special reference to anxiety treatment]

Investigations were made in more than 2,500 adult patients into desired effects and undesirable side-effects following an average premedication dosis of 6.1 mg midazolam administered intramuscularly. Particular interest was directed to the anxiolytic effect of this benzodiazapine. Midazolam proved to be an effective sedative and anxiolytic drug with no remarkable effects on vigilance and cooperation during induction of anaesthesia. Midazolam was well accepted by the patients and showed only slight side-effects.