Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pancreatic adenocarcinoma

T J Howard1

  • 1Indiana University Medical Center, Indianapolis, USA.

Current Problems in Cancer
|September 1, 1996
PubMed
Summary

Pancreatic cancer survival is improving due to surgical advances and chemoradiotherapy. Minimally invasive techniques offer palliation for advanced pancreatic cancer, enhancing quality of life.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Canadian Surgery Forum.

Canadian journal of surgery. Journal canadien de chirurgie·2022
Same author

Radiology of small bowel obstruction: contemporary approach and controversies.

Abdominal imaging·2005
Same author

Impact of pancreatic head resection on direct medical costs in patients with chronic pancreatitis.

Annals of surgery·2001
Same author

Roux-en-Y internal drainage is the best surgical option to treat patients with disconnected duct syndrome after severe acute pancreatitis.

Surgery·2001
Same author

Re: Stapfer M et al. Management of duodenal perforation after endoscopic retrograde cholangiopancreatography and sphincterotomy. Ann Surg 2000; 232:191-8.

Annals of surgery·2001
Same author

Classification and management of perforations complicating endoscopic sphincterotomy.

Surgery·1999

Area of Science:

  • Oncology
  • Surgical Oncology
  • Gastroenterology

Background:

  • Pancreatic carcinoma presents late, with limited treatment options and poor survival rates.
  • Radical surgical resection is the primary curative treatment, but only feasible for a small percentage of patients.
  • Past therapeutic nihilism is being replaced by a renaissance in pancreatic cancer treatment.

Purpose of the Study:

  • To review recent advances in pancreatic cancer diagnosis and treatment.
  • To highlight improvements in surgical techniques, adjuvant/neoadjuvant therapies, and diagnostic imaging.
  • To emphasize the role of minimally invasive techniques in palliation and improving quality of life.

Main Methods:

  • Review of surgical advancements, including pancreaticoduodenectomy with reduced mortality.
  • Integration of adjuvant and neoadjuvant chemoradiotherapy protocols.
  • Utilization of advanced imaging: endoscopic retrograde cholangiopancreatography, helical CT, endoscopic ultrasonography.
  • Development of percutaneous, endoscopic, and laparoscopic techniques for palliation.

Main Results:

  • Improved surgical outcomes and reduced perioperative mortality.
  • Enhanced diagnostic accuracy and staging with advanced imaging.
  • Effective palliation and improved quality of life for unresectable or metastatic disease.
  • Potential for long-term survival in a growing proportion of patients.

Conclusions:

  • Contemporary pancreatic cancer treatment has shifted from therapeutic nihilism to aggressive management.
  • Advances in surgery, chemoradiotherapy, and imaging offer improved outcomes and palliation.
  • Continued research into molecular genetics and aggressive patient recruitment are crucial for sustained progress.

Related Experiment Videos