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Morphometric study on the fetal thyroid gland in the nude mouse (BALB/cAnNCrj-nu/nu)
T Inomata1, H Ninomiya, S Kawakami
1Department of Laboratory Animal Science, College of Environmental Health, Azabu University, Kanagawa, Japan.
Experimental Animals
|October 1, 1996
Abstract:
Fetal thyroid glands of athymic nude mice (BALB/cAnNCrj-nu/nu) were examined morphometrically on day 18 of gestation. Compared to euthymic litter mate controls (BALB/ cAnNCrj-nu/+), both the cell height and diameter of thyroid follicles were significantly smaller; fewer well-developed follicles were found in the peripheral region of the thyroid; the body weight and total volume of the thyroid gland were also smaller in nude mice. These results suggest underdevelopment of the fetal thyroid gland of the athymic nude mouse.