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Development and Validation of a Quantitative PCR Method for Equid Herpesvirus-2 Diagnostics in Respiratory Fluids
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Development of immuno-PCR for diagnosis of bovine herpesvirus 1 infection

A S Mweene1, T Ito, K Okazaki

  • 1Department of Disease Control, Hokkaido University Graduate School of Veterinary Medicine, Sapporo, Japan.

Journal of Clinical Microbiology
|March 1, 1996
PubMed

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Herpes01:28

Herpes

Herpes simplex type 1 (HSV‑1) is a widespread pathogen responsible for orolabial lesions. It is an enveloped, double-stranded DNA (dsDNA) virus belonging to the family Herpesviridae. Once the virus infects a host cell, its double‑stranded DNA genome is delivered into the nucleus, where a coordinated cascade of immediate‑early, early, and late gene expression directs viral DNA replication, structural protein synthesis, and virion assembly. After primary infection of epithelial cells, HSV-1...