Neurological findings in the normal elderly: prevalence and relationships with memory performance

Data on the presence of neurological signs in the normal elderly are scanty, and data on their possible relationships to memory performances are not available. Three-hundred and ninety-six subjects born in 1925 and living in Pavia, who were recruited for a larger study on memory impairment in the elderly, underwent a standardized neurological examination (SNE) consisting of 22 items, an anamnestic interview and a memory test battery. A high number of signs was found, particularly for regressive reflexes (snout in 50% of cases). There was a tendency for several alterations to be found in the same subject. Accordingly, four clusters of signs were identified. Diabetes mellitus, hypertension, heart disease or past head trauma were not consistently associated with SNE scores. While memory impairment was also not consistently associated with SNE scores, there was a higher tendency for memory-impaired subjects to show at least one abnormal SNE score.