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Expression of feline immunodeficiency virus (FIV) gag gene in vaccinia virus vector
1Department of Carnivore and Fur Animal Diseases, National Veterinary Research Institute, Pulawy, Poland.
Acta Microbiologica Polonica
|January 1, 1995
Abstract:
The selected part of gag gene (nucleotide sequences at position 618 to 1724) coding for P24 and P15 proteins of feline immunodeficiency virus (FIV) was expressed in vaccinia virus vector under control of 7.5 kDa vaccinia virus transtriptional signal (p 7.5 vaccinia virus early/late promoter). The vaccinia virus recombinant (denoted VV-G(1)) was generated by homologous recombination following CV-1 cells transfection with a newly prepared vaccinia virus insertion vector -- pWKr75.