Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Uveitis in children

P Pivetti-Pezzi1

  • 1Ocular Immunovirology Service, University of Roma La Sapienza, Italy.

European Journal of Ophthalmology
|July 1, 1996
PubMed
Summary
This summary is machine-generated.

Pediatric uveitis, while less common than in adults, poses significant visual risks due to chronic inflammation and diagnostic challenges. Early identification of causes like juvenile rheumatoid arthritis and toxoplasmosis is crucial for better outcomes.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Changing patterns of ocular manifestations in HIV seropositive patients treated with HAART.

European journal of ophthalmology·2006
Same author

Prognosis of juvenile rheumatoid arthritis-associated uveitis.

European journal of ophthalmology·2003
Same author

Polymorphism of the Duffy erythrocyte chemokine receptor in Italian patients with Behçet's disease.

Rheumatology international·2003
Same author

Treatment of severe ocular hypotony in AIDS patients with cytomegalovirus retinitis and cidofovir-associated uveitis.

Ocular immunology and inflammation·2002
Same author

Chorioretinopathy and discoid plaque-like lesions of the eyelids as useful indicators of systemic lupus erythematosus (SLE) progression.

Lupus·2001
Same author

Indocyanine green angiographic findings in Behçet disease.

Retina (Philadelphia, Pa.)·2001
Same journal

Long-term smoking and early-onset diabetic retinopathy in young-onset type 2 diabetes.

European journal of ophthalmology·2026
Same journal

Optimizing mitomycin C in photorefractive keratectomy: A paired-eye comparison of 15- versus 30-second applications.

European journal of ophthalmology·2026
Same journal

Mendelian randomisation in ophthalmology: An overview and practical guide for clinicians.

European journal of ophthalmology·2026
Same journal

Association of interleukin-6 pathway inhibition with risk of age-related macular degeneration: A propensity-matched cohort study.

European journal of ophthalmology·2026
Same journal

Clinical characteristics of thyroid eye disease with restrictive strabismus.

European journal of ophthalmology·2026
Same journal

Predictive factors and development of traumatic angle recession glaucoma following blunt ocular trauma.

European journal of ophthalmology·2026
See all related articles

Area of Science:

  • Ophthalmology
  • Pediatrics
  • Rheumatology

Background:

  • Uveitis diagnosis is more frequent in adults, but pediatric cases present higher risks of chronic inflammation and poorer visual prognosis due to diagnostic delays.
  • Childhood uveitis classification is more successful (71%) than in adults (55%), with distinct age-related etiologies influencing diagnosis and prognosis.

Purpose of the Study:

  • To review the specific etiologies, diagnostic challenges, and prognostic factors of uveitis in the pediatric population.
  • To highlight the importance of early diagnosis and surveillance for specific pediatric uveitis subtypes and associated conditions.

Main Methods:

  • Literature review focusing on pediatric uveitis prevalence, causes, and clinical outcomes.
  • Analysis of etiological classifications and diagnostic difficulties in childhood uveitis compared to adult cases.

Related Experiment Videos

Main Results:

  • Juvenile rheumatoid arthritis is the leading cause of pediatric anterior uveitis (28%), necessitating surveillance, especially in ANA and HLA DR11 positive girls with pauciarticular disease.
  • Intermediate uveitis is largely idiopathic (98%) and a major cause of vision loss via cystoid macular edema; toxoplasmosis is the most common posterior uveitis cause (43%).
  • Diffuse uveitis forms are rare but severe, potentially indicating systemic diseases or masquerade syndromes like retinoblastoma or leukemia.

Conclusions:

  • Effective management of pediatric uveitis requires understanding age-specific etiologies and implementing targeted ophthalmic surveillance protocols.
  • Prompt diagnosis and management of pediatric uveitis, particularly infectious and autoimmune causes, are essential to prevent irreversible visual impairment.