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Benign prostatic hyperplasia. Does a correlation exist between prostatic morphology and irritative symptoms?

A Atan1, T Horn, F Hansen

  • 1Department of Urology, Herlev Hospital, University of Copenhagen, Denmark.

Scandinavian Journal of Urology and Nephrology
|August 1, 1996
PubMed
Summary
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Irritative symptoms after prostatectomy for prostatism are not linked to prostate characteristics. Bladder reactions, not prostate factors, likely cause these urinary irritative symptoms.

Area of Science:

  • Urology
  • Surgical Pathology

Background:

  • Prostatism, often treated with prostatectomy, can present with irritative voiding symptoms.
  • The etiology of these irritative symptoms post-prostatectomy remains incompletely understood.

Purpose of the Study:

  • To investigate potential correlations between irritative symptom scores and various clinical and histopathological parameters in patients who underwent prostatectomy for prostatism.

Main Methods:

  • Fifty-two consecutive patients undergoing prostatectomy for prostatism were assessed.
  • Data collected included irritative symptom score, age, prostate volume, urine culture, detrusor instability, prostatic inflammation, and histopathology (stromal, glandular, or mixed).

Main Results:

  • No statistically significant correlations were found between the irritative symptom score and prostate volume, age, detrusor instability, inflammation, or histopathological findings.

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  • Urine culture results also did not correlate with irritative symptoms.

    • Conclusions:

    • The study suggests that irritative symptoms following prostatectomy for prostatism are not directly associated with prostate-specific factors.
    • Extraprostatic factors, particularly bladder reactions, are likely the primary contributors to these symptoms.