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The effect of levenogesterol (Norplant) contraception on coagulation as measured by antithrombin-III levels
J A Pryor1, K R Cooper, J D Bass
1Department of Obstetrics and Gynecology, University of Mississippi Medical Center, Jackson 39216-4505, USA.
Purpose:
To determine the effect of contraception given immediately postpartum on coagulation as measured by antithrombin III.
Study Design:
In this prospective study, parturients (n = 85) self selected three means of postpartum contraception: levenorgesterol implants, oral contraceptives, or a barrier method.
Results:
Baseline coagulation was assessed by antithrombin-III levels in each of the 85 women within 48 hours of delivery (100.35 +/- 1.61%) and at one (109.1 +/- 1.89%) and six (105.51 +/- 1.71%) weeks postpartum. There was a rise in antithrombin-III after delivery but there were no significant differences between the groups.
Conclusion:
The levenorgesterol implant system did not cause a decrease in antithrombin-III in normal parturients.