Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hepatic resections in normothermic ischemia

G Nuzzo1, F Giuliante, I Giovannini

  • 1Department of Geriatric Surgery, Catholic University Medical School, Rome, Italy.

Surgery
|November 1, 1996
PubMed
Summary

Vascular occlusion during liver resection significantly reduces intraoperative bleeding and the need for blood transfusions. This technique is safe and does not lead to severe adverse effects on liver function.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Adequate lymphadenectomy and adjuvant capecitabine warrant survival benefit in gallbladder cancer.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2025
Same author

Return to sport after osteotomy in patients with hallux rigidus.

Foot and ankle surgery : official journal of the European Society of Foot and Ankle Surgeons·2025
Same author

Predicting early recurrence after resection of initially unresectable colorectal liver metastases: the role of baseline and pre-surgery clinical, radiological and molecular factors in a real-life multicentre experience.

ESMO open·2024
Same author

Development and validation of a comprehensive model to predict complications after hepatectomy.

European review for medical and pharmacological sciences·2024
Same author

Dragon 1 Protocol Manuscript: Training, Accreditation, Implementation and Safety Evaluation of Portal and Hepatic Vein Embolization (PVE/HVE) to Accelerate Future Liver Remnant (FLR) Hypertrophy.

Cardiovascular and interventional radiology·2022
Same author

Project for interventional Oncology LArge-database in liveR Hepatocellular carcinoma - Preliminary CT-based radiomic analysis (POLAR Liver 1.1).

European review for medical and pharmacological sciences·2022

Area of Science:

  • Hepatobiliary surgery
  • Surgical oncology
  • Transplantation surgery

Background:

  • Minimizing intraoperative blood transfusions is crucial in liver resections.
  • Temporary vascular inflow occlusion effectively reduces hemorrhage during hepatic resection.
  • Assessing normothermic ischemia's impact on bleeding and outcomes is essential.

Purpose of the Study:

  • To evaluate the effect of normothermic ischemia on intraoperative bleeding.
  • To assess the impact of vascular occlusion techniques on patient outcomes following hepatic resection.

Main Methods:

  • Sixty-one hepatic resections were analyzed.
  • Techniques included pedicle clamping and total vascular exclusion.
  • Mean normothermic ischemia duration was 40 minutes; major resections comprised 52.5%.

Related Experiment Videos

Main Results:

  • No operative mortality was observed.
  • Major complications occurred in 11.5% of patients.
  • 41% received transfusions (mean 2.4 units); 37.5% of major resections required no transfusion.

Conclusions:

  • Vascular occlusion techniques benefit hepatic resections by reducing bleeding and complications.
  • Routine use of these techniques, with precautions, is safe for liver function.
  • Normothermic ischemia is a valuable method for managing bleeding during liver surgery.