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Application of Long-term cultured Interferon-γ Enzyme-linked Immunospot Assay for Assessing Effector and Memory T Cell Responses in Cattle
Published on: July 11, 2015
Reduced mitogenic responses in cultures of lymphocytes from newly calved cows
The proliferative responses to stimulation with phytohaemagglutinin (PHA) in cultures of lymphocytes from newly calved and non-pregnant cattle were compared. Lymphocyte cultures from newly calved cows were seen to respond less to PHA than cultures from the non-pregnant cows. It is suggested that this depression in responsiveness of lymphocytes in the immediate post-parturient period may be involved in the etiology of disease in cattle during the immediate post-parturient period.
The proliferative responses to stimulation with phytohaemagglutinin (PHA) in cultures of lymphocytes from newly calved and non-pregnant cattle were compared. Lymphocyte cultures from newly calved cows were seen to respond less to PHA than cultures from the non-pregnant cows. It is suggested that this depression in responsiveness of lymphocytes in the immediate post-parturient period may be involved in the etiology of disease in cattle during the immediate post-parturient period.
