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Puberty and menarche

A F Goldfarb

    Clinical Obstetrics and Gynecology
    |September 1, 1977
    PubMed
    Summary

    Puberty and menarche are influenced by a complex interplay of genetics, hormones, nutrition, and environmental factors from intrauterine life through prepubertal years. These multifactorial influences shape adolescent development and culminate in the onset of menstruation in females.

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    Area of Science:

    • Pediatric endocrinology
    • Human development
    • Reproductive health

    Background:

    • Puberty and menarche are critical developmental milestones influenced by numerous factors.
    • These influences originate from intrauterine life and extend through prepubertal years.
    • Understanding these factors is crucial for assessing normal adolescent development.

    Purpose of the Study:

    • To elucidate the diverse factors impacting puberty and menarche.
    • To highlight the environmental and biological determinants of adolescent development.
    • To provide a comprehensive overview of influences on female reproductive maturation.

    Main Methods:

    • Review of existing literature on factors affecting puberty and menarche.
    • Analysis of genetic, hormonal, nutritional, and environmental influences.
    • Synthesis of data on prepubertal and intrauterine developmental factors.

    Main Results:

    • Genetics, hormones, and nutrition are key intrauterine influences.
    • Health, disease, family environment, and neuroendocrine function are critical prepubertal factors.
    • Menarche represents the culmination of these multifactorial influences in females.

    Conclusions:

    • Puberty and menarche are complex processes shaped by a holistic environmental and biological context.
    • Early life factors significantly impact the timing and progression of reproductive maturation.
    • A comprehensive understanding of these influences is vital for pediatric and adolescent healthcare.

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