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Rapid opiate detoxification

T Bartter1, L L Gooberman

  • 1Chronic Pain and Addiction Center, Merchantville, New Jersey, USA.

The American Journal of Drug and Alcohol Abuse
|November 1, 1996
PubMed
Summary
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Rapid opiate detoxification (ROD) offers an effective and efficient method for treating heroin addiction. This approach significantly abbreviates traditional withdrawal schedules in a controlled clinical setting.

Area of Science:

  • Addiction Medicine
  • Pharmacology

Background:

  • Opiate addiction presents a significant public health challenge requiring effective treatment strategies.
  • Traditional opiate withdrawal protocols can be lengthy and associated with significant patient discomfort.

Purpose of the Study:

  • To evaluate the clinical and practical aspects of rapid opiate detoxification (ROD) for heroin addiction.
  • To assess the efficacy of ROD in abbreviating the traditional withdrawal schedule.

Main Methods:

  • Twenty-five heroin-addicted patients underwent 29 detoxification procedures using various ROD techniques.
  • ROD involved inducing withdrawal with narcotic antagonists and suppressing symptoms with sedatives in a controlled environment.
  • Different sedation methods, including intravenous sedation, paralysis, and intubation, were employed.

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Main Results:

  • Rapid opiate detoxification (ROD) was successfully implemented in all but three cases.
  • All patients undergoing ROD demonstrated effective detoxification, with no withdrawal symptoms reported post-treatment.
  • Naltrexone administration prior to discharge confirmed the absence of withdrawal symptoms in treated patients.

Conclusions:

  • Rapid opiate detoxification (ROD) is a valuable, efficient, and effective tool for heroin addiction treatment within integrated rehabilitation programs.
  • The optimal method for ROD requires further determination, with a range of approaches available.
  • Rapid opiate detoxification (ROD) may be best suited for specialized outpatient centers.